The making of the world’s first needle-free glucose monitor
How it works?
We developed a platform technology that uses magneto-hydrodynamics to gently transport molecules without needles or breaking the skin. For detection, we rely on well-established enzymatic biosensing chemistry — trusted for decades in glucose monitoring and capable of medical-grade precision.
Through careful integration of physics, biology, and engineering, these components work together to enable accurate, needle-free glucose monitoring.
High quality sample
Put simply, Sofio acts like a glucose magnet. When activated, its patented magnetohydrodynamic technology draws glucose-containing interstitial fluid gently through the skin — without needles. The glucose levels in the fluid are then analysed.
Modular design
Sofio has two parts: a reusable transmitter and a replaceable sensor. They connect through a simple plug-and-play mechanism, and the sensor attaches to the skin using a peel-and-stick method.
Ultra sensitive detection
A thin, enzymatic biosensor measures the glucose in interstitial fluid with medical-grade precision. Feather-light: the transmitter weighs 22 g and the sensor 2 g.
Built for scale
The transmitter contains all electronics and can be reused hundreds of times.
The sensor uses a tiny enzyme-based sensing film instead of electronics, making it clean to manufacture at scale and affordable to replace.
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Tried and tested, thousands of times
Sofio’s technology has been used and tested by hundreds of people in the past 6 years and has undergone tens of thousands of laboratory tests to ensure performance, safety, and consistency.
Scientific publications
April 2021: INTRODUCTION OF MHD. Sampling of fluid through skin with magnetohydrodynamics for noninvasive glucose monitoring.
November 2022: MHD – THE FIRST HUMAN PILOT. Pilot study in human healthy volunteers on the use of magnetohydrodynamics in needle-free continuous glucose monitoring.
June 2022: ULTRA-SENSITIVE BIOSENSOR, COMPATIBLE WITH MHD. Influence of enzyme immobilization and skin-sensor interface on non-invasive glucose determination from interstitial fluid obtained by magnetohydrodynamic extraction.
December 2025: NEW DISCOVERY ENHANCING GLUCOSE DETECTION ACCURACY. Use of Prussian Blue pseudocapacitive properties to amplify the pulsed amperometric readout of biosensors.
April 2021: INTRODUCTION OF MHD. Sampling of fluid through skin with magnetohydrodynamics for noninvasive glucose monitoring.
November 2022: MHD – THE FIRST HUMAN PILOT. Pilot study in human healthy volunteers on the use of magnetohydrodynamics in needle-free continuous glucose monitoring.
June 2022: ULTRA-SENSITIVE BIOSENSOR, COMPATIBLE WITH MHD. Influence of enzyme immobilization and skin-sensor interface on non-invasive glucose determination from interstitial fluid obtained by magnetohydrodynamic extraction.
December 2025: NEW DISCOVERY ENHANCING GLUCOSE DETECTION ACCURACY. Use of Prussian Blue pseudocapacitive properties to amplify the pulsed amperometric readout of biosensors.